产品货号：
Z17899
中文名称：
HSP47/SERPINH1抗体
英文名称：
Anti-HSP47/SERPINH1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HSP47/SERPINH1 Antibody |
| 指标别名 | 47kDa heat shock protein;AsTP3;CBP1;CBP2;Colligin;gp46;HSP47;PIG14;PPROM;RA A47;Serpin H1;SERPINH1;SERPINH2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | SERPINH1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Hsp47 recombinant protein (Position:D247-L418).Human Hsp47 shares 97% amino acid (aa) sequence identity with both mouse and rat Hsp47. |
| 实际分子量 | 46KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Heat shock protein 47,also known as SERPINH1 or HSP47,is a serpin which serves as a human chaperone protein for collagen.This protein is a member of the serpin superfamily of serine proteinase inhibitors.Its expression is induced by heat shock.The protein localizes to the endoplasmic reticulum lumen and binds collagen;thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules.Autoantibodies to this protein have been found in patients with rheumatoid arthritis.It has been found that HSP47 monitors the integrity of the triple helix of type I procollagen at the ER/cis-Golgi boundary and,when absent,the rate of transit from the ER to the Golgi is increased and the helical structure is compromised. |
| Uniprot ID | P50454 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | serpin peptidase inhibitor,clade H (heat shock protein 47),member 1,(collagen binding protein 1) |
| 蛋白名全称 | Serpin H1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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